One should be at the bottom one at the top. I understand space on the phone is a premium but a second port would make the phone so much more usable. Wired headphones, flash drives, camera modules, speaker modules, keyboards, even connection to a TV, all could be used while charging. It's a shame it's not a thing, USB is extremely versatile port, but you only get one and it's used for charging half of the time. (I am aware dongles exist)
I agree with this idea. But it would make it harder to pick up your phone blindly and know which end is the top. I instinctively feel for the usb port on the bottom so it's oriented correctly by the time my arm swings it into view.