In November my doc put me on Jardience to help control my diabetes, and it was working very well. I was able to cut my insulin usage in half scale-wise, but also my urge to snack was way down further reducing my need for insulin. On December 23rd I had a complete reversal... of my digestive tract. I was throwing up and couldn't even hold down water. This persisted for about 5 days, until I was able to tolerate half a slice of peanut butter toast and a few sips of coffee. My gf's sister had had a similarly bad reaction to Ozempic earlier this year and her boyfriend recently ended up in the hospital with a ruptured ulcer in his stomach (also on Ozempic).

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[–] 15 points 7 months ago

First and foremost, talk to your doctor ASAP if you haven't already.

Personally, I'm on Mounjaro and I get diarrhea periodically. I get it more frequently when my dosage goes up, so when I get to the point where I don't have it anymore, I take it as a sign that I may need to have my doc up the dosage again.

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  • [–] 7 points 7 months ago

    I had similar reactions to GLP-1s (for diabetes). If the symptoms don't go away within a few weeks, you may want to talk to your endocrinologist about the issue. Sometimes, just increasing or lowering the dose can help. For me, Ozempic was the worst. I am now on Mounjaro, and no longer have any problems. Everyone is different, though.

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  • [–] 5 points 7 months ago

    Purely anecdotal but Mike Israetel had some arguments for waaaay lower doses than what is prescribed. Talk to your doctor of course. I think this might be be the video. https://m.youtube.com/watch?v=matVhd7k25w

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  • [–] 3 points 7 months ago (1 child)

    Hi, just wanted to clarify in case I read this wrong but Jardiance (empagliflozin) is a SGLT2 inhibitor, not a GLP-1. Ozempic (semaglutide) is a GLP-1.

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