I’ve been using AdGuard for some time. It works really well for me.

Pi-hole for my whole network, I can WireGuard into it when I'm away.

AdGuard on the iphone and nextdns.io for DNS is a very effective combo. I also use StopTheMadness to eliminate a lot of annoyances, especially google's shitty amp links.

Adguard plus iCloud Private Relay is hard to beat for me.

Ad Guard in Safari. When you get a site that says you are being naughty, you flip to “Show Reader” to bypass.

Then install Sink It and you’ll miss out on all the cookie prompts and bs, including Reddit asks to install app (I no longer have an account there).

For safari i use Firefox Klar and Hyperweb as Extensions.

Other than that I have a raspberry pi running WireGuard and Pi-hole, which my phone is constantly connected to. This provides extra security (as all my traffic is encrypted) and privacy. Pi-hole filters out ad and tracking domains.

I use the ad blocking built into Proton VPN. That way my traffic stays private and no ads/trackers.

I use a pihole on my network with a VPN for when I'm out and about

I’ve been using Wipr, but the cookie notice blocking is breaking quite a few sites now

NextDNS. Setup on my router so it hits all devices.

Pihole on my Debian system with PiVPN WireGuard server.

Safari extensions:
Vinegar to block YouTube ads in Safari. I don’t use the app at all.
Banish to stop websites showing those annoying “open in the app” pop ups.

Ad and nag free bliss.

I use Brave browser, which has ad and tracker blocking built in.

I also have all my devices using a piHole for ad, malware, and tracker protection.

Seconding AdGuard . It’s really working well for me.

I use Adguard as well, especially when I let my YT premium lapse, their extension to play a video PIP with no ads from the share sheet is awesome.

Another AdGuard user here. I’ve got the paid pro version that allows DNS blocking system wide via the VPN profile method but if you’re just looking for Safari only the free version is good.

Firefox focus. It can be set as ad blocker not just as a history deleting browser. I use Firefox as my main browser on ios, but I don’t really see ads anywhere phone-wide

Adguard pro along with adguard home.

Installed adguard based on all the good reviews here!

AdGuard

1Blocker and a pihole at home.

Aha DNS Blitz. Instead of an app, you install a VPN profile. The benefit is that it protects you wherever you go regardless of the connection you're using (home wifi, mobile data, public wifi, etc.).

Control D is a great versatile DNS level ad and tracker blocker. You can also route specific services to different exit locations, so stuff like Netflix can think you're in the US.

Wipr + NextDNS

Adguard DNS

Unicorn

Legacy 1Block, and the orion browser as a supplement.

Brave Browser, by far the best and so customizable. Many people don't check settings but on mobile view the security > filters and you can enable the mobile YT script blocks for more ad-blocking and clearer look!

And I use Proton VPN w/ Block Ads, Trackers & Malware, but not really required.

For just Safari the "Roadbock" extension seems to work pretty well.