Factoring in marketing costs and the theaters taking their cut of the profits, Megalopolis would need to make at least $300 million to break even. I think it's safe to say that's not happening.
It would have been THE worst opening for a $100 million movie ever, had it not been for Pluto Nash's horriffic opening 22 years ago.
The trailer made it seem like the kind of pretentiously boring mess that the director seemed to think had some profound message that I tend to really dislike.
Or put more simply, "Looks like the director set $120 million on fire to win Oscars, not make something entertaining."