Sure, like I said above, GOS doesn't at all prevent you from rooting the device. They only discourage it from a security point of view. Regarding MicroG, I've never had need for it myself but I've read many other posts over the years from users who have installed it on GOS in lieu of Graphene's own implementation.
I would argue that overall GrapheneOS provides more control over the OS than some other Android-based operating systems.