possible
In practice? No not really.
JShelter is the only thing I have seen that stops creepjs from working at all. But that doesn't mean you can't be fingerprinted. Not to mention Crimeflare has been very successful with their TLS fingerprinting methods (among other things), which doesn't even require working JavaScript.
And compared to creepjs, EFF's tool is a joke and works quite differently, and not in a good way.