(paraphrased from memory, not verbatim) Adhd is a genetic condition which warrants genetic therapy. Stimulants work well for this but they only work while it is in the bloodstream.
-- Dr. Russel Barkley, paraphrased from one of talks on adhd
Personally different stimulants have different effects on different people. On Ritalin I am super chatty but cannot focus. On adderall/vyvanse I am not always chatty but I can focus. The generic of vyvanse is supposed to be out soon and if anyone is looking for all day meds but want something a little more gentle than the come up of adderall definitely talk to your doc. Tangent, but vyvanse has an interesting delivery mechanism: its a prodrug that turns into a stumulant in your GI tract. As such, it uses your digesting of food throughout the day to produce more stimulant. One advantage of vyvanse is that it cannot get you high if it is snorted (which helps alleviate the concern of abuse) because it must be made into a stimulant in your body. The big problem with vyvanse for a while has been that it's non-generic and something like $400 a month if paid out of pocket.