This is one of my pet peeve misspellings, so I apologize but I can’t help myself. It’s impossible to “effect” anything as it’s only ever a noun. Effects are the result of someone affecting something. For instance, someone can affect a justice, the effect being that they hold sway over the daily lives of many Americans despite the absence of credentials.

I don’t believe any of their spouses set out to do so when they married them but they certainly do so to the detriment of humanity at large, and that’s bad enough.