Just to be well and truly fuckin clear. I am not now nor have I ever been nor will I ever be contemplating shagging a family member.

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[–] 63 points 2 years ago (1 child)

I am a carrier of CFTR mutations. If I knock up a random woman theres a 1 in 80000 chance of the child having cystic fibrosis. If I knock up my sister theres a 1 in 16 chance instead.

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  • [–] 27 points 2 years ago (2 children)

    I'm being pedantic, but if you know you're a carrier (and don't know the carrier status of your sister) then it is 1 in 8

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