I can see how that would be a selling point for a lot of groups, but most D&D-style rpg players I've played with don't really think about RPGs as a way of playing in cinematic universes that aren't relatively generic fantasy. Even my slightly steampunk-ish 1800s-style homebrew setting that I used for D&D and now use for PF2e often throws my players for a loop.

Edit: also, Starfinder 2e is coming soon and is planned to be built in the same mechanical system as PF2e, meaning that the two systems will be compatible. So that idea of a generic system for different genres of fiction is not going to be as unique.