If you like Sawbones you might also like "This podcast will kill you", an epidemiologist and a doctor make cocktails and go into the history and pathophysiology of diseases and conditions throughout human history.

Not as classically funny as the McElroys, but really informative and they do a good job at keeping the "disturbing content" to a minimum even when going into detail on pretty devastating illnesses.

For a much more lightweight podcast "You're Dead to Me" from the writers of Horrible Histories is fun. A historian quizzes comedians on their knowledge of historical events and figures.