Out of the box it can play audio in the background, and now that extensions are available you can block ads as well. You don't really need constantly updating 3rd party clients or questionable firewalls anymore if you just want usable youtube on a phone.
Significantly easier? Newpipe is simply installed from fdroid. I've only looked for a few minutes but it looks like revanced "patches" YouTube. Does that mean it doesn't create its own app but overtakes another? How does that interact when the app underneath gets a play store update?