The release of qBittorrent v4.6.0 stable comes with I2P support. While experimental, we can still get a working torrent setup using qBittorrent now. qBittorrent-nox is the Web-UI only version, and currently it does not have configuration settings in the Web-UI for I2P settings. This guide will show you how to setup qBittorrent-nox and manually change the qBittorrent.conf file to allow for I2P torrenting!
Yes, I did exactly this when I2P support was first in beta. I have a docker stack with Gluetun as my network for all my *arr containers and I was able to still point my qBittorrent to my i2pd router and it worked just fine.