I've heard dual booting Linux and Windows isn't a good idea because Windows Update will nuke the Linux boot loader, so I've avoided doing that.

For a very long, technical, and complicated reason, I still need Windows because one piece of software that I absolutely MUST have is only compatible with Windows. No, there is no alternative software available for my use case; none, zero, not any, at all. I've already tried running it within many different VMs, using many different hypervisors, and I've already tried Wine; they aren't an option, the software isn't stable in those cases. I don't want to get in the weeds about it, so please just accept that I NEED some version of Windows installed.

Since Windows 10 doesn't receive updates anymore, can I dual boot Linux and Windows 10 without worrying about whether Windows Update will break anything? I intend to keep Windows on one drive and Linux on another. Windows would only be used when I need to run this one specific program, which is maybe five or ten hours per week. The rest of the time, I'd be using Linux.