Might I introduce you to the good old Dutch tradition of swearing with diseases?

Tuberculosis ("tering!"), typhoid ("tyfus!"), cholera ("klere"), mange ("schurft"), smallpox ("pokken") are pretty cool and acceptable. Cancer used to be common but that's rather fallen out of fashion. You can also combine it with religious swearing AND reproductive organs for a trifecta.

"Godverdetyfuskutzooi" is just a beauty, but "goddamtyphoidvaginamess" doesn't work in English.