I've tried Affinity, it's got a few dealbreakers.

No ability to save a workspace or have it be cohesive across projects. Searched online to see if there was a fix for it and there's not, you just have to set up your desired workspace for every single new project you start. Controls are not intuitive, i.e. right click does not bring up brush size menu. Can't select parts of the drawing and just flip horizontal/vertical, you have to put it on a new layer and do a bunch of extra stuff to flip it. Also tried to import my PS brushes into Affinity and a lot of them had broken or mangled textures or just, did not operate the same and no amount of finagling could restore them to how they were.

I really wanted to like it but it's still got some kinks that need to be worked out.