I'd use it to kill platforms.
HTML5 is a fine executable format. Electron sucks because it bundles a browser with each webpage. The technical hurdles are smaller than the mountain of usability issues we'll have to sand down, to make "web apps" Just Work. Native apps will always be better, but we've accidentally done a Java with write-once-run-everywhere, and it's ridiculous how poorly we've used that.
On the back end, we have nearly-invisible translation layers like WINE and fairly efficient emulators like BOCHS, so there's no reason Windows apps shouldn't run on everything. x86, ARM, RISC-V, whatever.
SPIR-V should already let you treat the GPU like a zillion-core CPU. Nvidia's CUDA bullshit has gone on too long.
And then drop in some not-quite-emulators for consoles, since they're just PCs anyway. End the charade.