The main target of the Godot Engine are game developers. But Godot's easy workflow and functional UI elements, makes it also a good fit for non-game applications. There are already some out there you may know, like Pixelorama, an Open Source 2D sprite editor.
I know many Mac users who use Safari just because it’s doesn’t drain the battery as much as Chrome. That's a big difference for desktop applications, and constantly redrawing the window at 60fps definitely will kill your battery.