I haven't watched the show (I heard that it isn't very good) but I loved the books. With that said, Asimov's writing never seems concerned with gender-specific behavior or interactions between men and women. If I recall correctly, every major character in the trilogy is male, but I think that was just the default assumption at the time the books were written and Asimov had no interest in analyzing that assumption. Therefore, simply changing some characters to women can make the story more realistic to a modern audience while preserving everything important in the books (as long as there aren't romance subplots, because Asimov characters are incapable of romantic love).