Bob is marginalised in a way invisible to the people around him, but it's there. As a plus size person, he doesn't fit in his cubicle or his car. When he stops paying attention, the world around him crumbles. World of cardboard. Being huge and super strong isn't easy for him.
But what's even harder is having Bob's justice sensitivity. Justice sensitivity is a symptom of autism in which neurodivergent people are more sensitive to social problems. Bob gets fired because his sense of right and wrong is too strong to fit into the world around him.
Dash also struggles with the same problems as neurodivergent people. Dash's allegory is ADHD. He's not allowed to participate in the parts of school life that interest him; that he's good at. He's constantly holding himself back. I was a gifted kid too, and my giftedness has caused consequences for other students when I dominated a classroom discussion. When I was moved to a gifted school and surrounded by peers, life got better for me. I see myself in Dash.
Violet's marginalisation is more of an immigrant/racialised/misogyny problem. She's accepted the mainstream narrative that her powers make her a freak. That she's different and that's bad. That normality is an ideal to aspire to. She becomes confident in herself after she's allowed to engage with her own native culture and see that it's not bad. She gets a talk from Mum and forges a new relationship with her minority identity. The fighting is secondary. The story isn't about it.
There are queer or disabled people in white middle class nuclear families, and they have problems. I think Brad chose to make the story relatable to everyone by using a cultural image we're very familiar with. But then he showed problems that happen when someone, even someone in that social role, is different from what society expects.