I think sci-fi has it right with that, I mean you'd only get up out of your chair or whatever receptacle to perform bodily functions. Most people think everyone would turn into fat blobs, but I think that's not the case. There's this one sci-fi where I think they got it right, most people became emaciated due to a failure to eat and get any exercise.
Oh and I'll take the blue pill, VR all the way, reality blows. Though some might say reality is already virtual. It's an interesting hypothesis, sure would explain a lot.