I’ve had the Advantage360 for 6 months or so and it’s life changing when typing for 10 hours a day. Haven’t gotten around to relearning on Dvorak or Colmak layout as I learnt qwerty on the 360 first.

I recently bit the bullet and bought a Kinesis Advantage360. Definitely interesting to get use to and eye wateringly expensive, but my wrist pain went away within days.