Sure, it's not 100% better in all situations. But when you're unfamiliar with something, almost universally, it's far more intuitive.
And this doesn't even take into account things like gaming. I also can't imagine trying to do visual design things solely with the computer. Like any type of drawing or schematic design.
Being pretty adept at using the keyboard, I'm often frustrated when I find out that the only way to do something is by mouse when there appears that there should be an easy way to do it by keyboard. But, man, I can't imagine longing for the days before the mouse.