▲ 219 ▼ Why a highly mutated coronavirus variant has scientists on alert (www.nature.com) submitted 2 years ago by Daryl76679@lemmy.ml to c/worldnews@lemmy.ml 9 comments fedilink hide all child comments
[+] doom_and_gloom@lemmy.ml [B] 15 points 2 years ago* (last edited 2 years ago) (1 child) [deleted] permalink fedilink source parent hideshow 2 child comments replies: [–] notacat@mander.xyz 11 points 2 years ago (2 children) T cells. “Most studies on COVID-19 vaccines have focused on neutralizing antibody (NAb) responses, with little emphasis on cellular immunity. However, accumulating data suggest that T cell responses play an important role in vaccine protection against severe COVID-19 disease, particularly against viral variants that partially escape from recognition by NAbs. These insights have implications for using current COVID-19 vaccines and for developing next-generation vaccines against COVID-19 and other infectious diseases” science permalink fedilink source parent hideshow 4 child comments replies: [–] currentbias@open-source-eschaton.net 9 points 2 years ago* @notacat speaking of those -- there is evidence that SARS-CoV-2 sticks around and causes chronic T cell activation, and there are only so many naive T cells the thymus can supply before it shrinks (it normally shrinks with age) This implies that all covid infections, even those that don't produce obvious long covid at first, may be prematurely aging the immune system https://www.medrxiv.org/content/10.1101/2023.07.27.23293177v1.full permalink fedilink source parent [+] doom_and_gloom@lemmy.ml [B] 8 points 2 years ago* (last edited 2 years ago) [deleted] permalink fedilink source parent
[–] notacat@mander.xyz 11 points 2 years ago (2 children) T cells. “Most studies on COVID-19 vaccines have focused on neutralizing antibody (NAb) responses, with little emphasis on cellular immunity. However, accumulating data suggest that T cell responses play an important role in vaccine protection against severe COVID-19 disease, particularly against viral variants that partially escape from recognition by NAbs. These insights have implications for using current COVID-19 vaccines and for developing next-generation vaccines against COVID-19 and other infectious diseases” science permalink fedilink source parent hideshow 4 child comments replies: [–] currentbias@open-source-eschaton.net 9 points 2 years ago* @notacat speaking of those -- there is evidence that SARS-CoV-2 sticks around and causes chronic T cell activation, and there are only so many naive T cells the thymus can supply before it shrinks (it normally shrinks with age) This implies that all covid infections, even those that don't produce obvious long covid at first, may be prematurely aging the immune system https://www.medrxiv.org/content/10.1101/2023.07.27.23293177v1.full permalink fedilink source parent [+] doom_and_gloom@lemmy.ml [B] 8 points 2 years ago* (last edited 2 years ago) [deleted] permalink fedilink source parent
[–] currentbias@open-source-eschaton.net 9 points 2 years ago* @notacat speaking of those -- there is evidence that SARS-CoV-2 sticks around and causes chronic T cell activation, and there are only so many naive T cells the thymus can supply before it shrinks (it normally shrinks with age) This implies that all covid infections, even those that don't produce obvious long covid at first, may be prematurely aging the immune system https://www.medrxiv.org/content/10.1101/2023.07.27.23293177v1.full permalink fedilink source parent
[+] doom_and_gloom@lemmy.ml [B] 8 points 2 years ago* (last edited 2 years ago) [deleted] permalink fedilink source parent