Not for PC games.

I remember things like... Different ammo types in Fallout not actually working correctly. Armor Piercing rounds actually do less damage because the calculation is fucked up in the code. Or the biggest fuck up: The slides playing incorrectly if you manage to solve the Gecko/Vault City issue flawlessly. It still plays the ending cards as if you sided with Vault City, instead of getting them to work together peacefully by replacing the president of VC.

Many infinity engine RPGs have game breaking scripting bugs that needed patching or still haven't been fixed even through user mods.

Anarchy Online straight up couldn't be installed because the physical media was screwed up. Bought it day 1; didn't play it until a full year after release when they finally put a fixed installer up for download.

World of Warcraft: Burning Crusade had an issue much like AO's, with physical media being printed incorrectly and not working.

Just go and find playthroughs of some of these old classics. They just work around the issues. That's what you had to do. In some cases, like soloing BG1 and 2, these issues were the only reason challenges were possible. lol