My biggest complaint is that we can’t just let a more appropriate character take over a conversation. One of my clumsy, dim-witted brawler friends runs ahead by one pixel triggering a cutscene, and I can’t jump in mid-conversation to smooth things over with my bardic talent. This is our most common reason for loading a previous save.

Yeah, we were running into this in my game with my buddy; I'm definitely the dumbass running ahead because I've got stealth and dex for scouting, but invisible cutscene/conversation triggers keep catching us and my dunce of a character gets stuck talking to the punters. It's kind of frustrating that the game encourages players to specialize in that way, but then makes it rather hard to take full advantage of that specialization if you don't set up the encounter absolutely perfectly.

The other one where that happens is that when a combat encounter ends with dialogue - first Auntie Ethel fight, say - the game picks the character who had the last turn as who Auntie is talking to when the conversation starts. In that case, it's almost always the party member doing big damage that pushed her past the damage threshold, and they're generally not built for talking to people.

Those get even more frustrating because there's an interface option to swap who's talking, but it doesn't seem to actually work in the majority of important conversations. It's only when talking to filler characters that I can hot-swap who's talking. I'd also love if, in addition to that button working more consistently - it'd tell you if someone in the party has 'unique' dialogue options for that moment. I think that having the whole party participate in conversations is chaotic and hard to implement in multiplayer - but a better capture of how those same interactions 'would' play out in a D&D game.

Second biggest complaint is the number of things that you can mis-click to destroy your character’s reputation. I’d love to be able to opt-in to an “are you sure” dialog when you accidentally click a random item on the floor while moving around.

It's very frustrating to get a whole faction pissed at you due to misclicking some 'owned' container or accidentally dragging a barrel. Gith creche was a nightmare for that, because every room and hallway is decorated with owned containers. Some measure to make it harder to accidentally loot someone's mold cheese while they're standing right in front of you would be really valuable.