Enterprise isn't exactly a representative sampling of star trek.
In TNG the only reoccurring villains that are more advanced than humans are the Q and the Borg. The iconians were super advanced, but are long dead. There are random space babies/sentient nebulas but most species are behind the federation in tech. Even the romulans aren't more advanced, just focused on war.
If you ever wonder how advanced humanity is in star trek, remember that Q is a reoccurring villain. Q has complete control of space, time and reality. The federation is so advanced God is an antagonist.