Finding a Webpack replacement that doesn’t use NPM at all is going to be hard, but there are certainly alternatives that don’t require the 1000+ NPM dependencies required to use Webpack.
Some alternatives you can consider are Rsbuild and Farm. Part of the reason they use so much fewer NPM dependencies is because they’re written in Rust, so they’ll have Cargo dependencies instead, but you shouldn’t notice anything of that. Of course if you want to audit everything it’s not that much easier, but at least the Cargo ecosystem seems to have avoided quite some of the mistakes that NPM made. But yes, in the end it still comes down to the extent that you trust your dependencies.