Looks like there are some security, privacy and stability advantages. But for most people systemd should be fine.
See here for further info:
https://madaidans-insecurities.github.io/guides/linux-hardening.html#choosing-the-right-distro
https://forums.whonix.org/t/fixing-the-desktop-linux-security-model/9172/2
https://www.unixsheikh.com/articles/systemd-isnt-safe-to-run-anywhere.html
https://unixsheikh.com/articles/the-real-motivation-behind-systemd.html
https://suckless.org/sucks/systemd/
https://without-systemd.org/wiki/index_php/Arguments_against_systemd/
https://nosystemd.org/
Edit: also getting dnscrypt to work with systemd is pretty tough and unreliable in my experience (debian and opensuse). See here https://github.com/DNSCrypt/dnscrypt-proxy/wiki/Installation-linux
This could be a problem if you are planning to use encrypted dns.