Yes but from the very beginning, Eddie Brock's Venom would protect who they (their chosen pronouns) considered innocent. They would use extreme measures to do it though like killing a mugger. So from the start, he always tried to do good.

I would definitely put Deadpool in this category though. Deadpool was first introduced by taking out the X-men. A couple of miniseries of him going up against the Juggernaut, people asked more from him. The "merc with the mouth", which seemed like a villain rip off of Spider-man, turned to a psycho then to a good guy through a change of heart. His character changes with each new series.