I pretty much exclusively stay at Embassy Suites when traveling with the family so the children have a separate room and fold out couch and I almost never (regardless of city) have had to pay more than $200 per night... Usually closer to $150.
I've stayed in a few Airbnbs also over the years and they've gotten so expensive that there's almost never a comparable value available anymore, especially on short notice.
And that's not even really taking into account the excellent breakfast and Manager's reception (with free drinks and snacks) that are included or for that matter the pool and hot tub at Embassy.
Maybe if you've got a really large family and need multiple rooms for your kids or something but otherwise I just don't see it.