I don't reload combat unless I totally wipe, or want to start the fight over entirely.
I reload most of the other checks because failure is rarely interesting here, there's no fail forward or succeed with cost. It's especially irritating when my character flubs a roll they have like +10 on.
I don't typically reroll stuff that has a very high dc that feels like my character couldn't do. Like if there's a DC 20 check and I have a +1, I'll probably just accept the loss.
I'd rather it was like fo:NV where you either have the skill or you don't.