Fortunately for us, this one isn't too likely, because realistically, an alien civilization capable of travelling the relevant distance and destroying another civilization isn't something that can be hidden from. They should be able, fairly easily, to examine every planet in the galaxy and see which ones have life on them, and wipe it out before any civilization ever arises at all. The fact that we exist at all necessarily implies that nobody in this galaxy has been committed to going this, at least for the past billion years or so.