The people in Arab countries are generally anti imperialism but the leadership can often to be beholden to America through (usually oil based) financial ties. Egypt’s government, for example (because it’s freshest in mind), has repeatedly tried to crack down on pro Palestine protests likely at the behest US handlers. They’re obviously not quite as heavily controlled as Israel, though one could argue that Israel has slipped the leash a bit lately, and Israel’s destruction would be a huge blow, but I don’t feel it would be the killing stroke you and I would like it to be.