For me its way easier to use a different browser for each use case. Librewolf for something, Mullvad for something else, also Brave, also Vivaldi. 4 different browsers are making my life seriously easy. Why would I stick to 1 browser with many profiles? If something breaks in that one browser (which happens quite often) all I have to do is fire up a different one and try again. Different people different use cases, different streamlines.