I've always heard that until you're master/GM level, it's better just to play it out. Your opponent might blunder too, or accidentally stalemate you. At the very least, it's good practice playing at a disadvantage. I know I've blundered huge leads myself, so who knows what's going to happen?

There's a psychological thing where we always assume that our opponents in games will never mess up, which makes it feel easy to give up the moment you make a mistake.

You don't have to resign at any point. Losing your queen isn't a reason to resign on its own. I resign when I can't see a way to avoid losing and I believe my opponent is very unlikely to blunder their win away.

If you want to play out the game then you should. I feel like you agree to play for the time on the clock, so if your opponent feels like they're wasting their time, then that's their own problem and not your fault.