It's kind of funny hearing you say that when some of the most famous paintings and statues are of people's naked bodies. I'm not saying I'd do it or that people would want me to or that they won't regret it any less than I regret some of the decisions I've made, but the biggest negative impact from doing so is social stigma from people who think doing so makes you less valuable. I'll leave it up to you to decide if you're going to stigmatize adults who are making choices about their life that pose no harm to anyone who hasn't consented.