Indeed, depending on various conditions, quite a few threads can end there on the spot. Other consequences (like losing the necrotic resistance) can be severe, too.
As is, I think the fight is probably too challenging considering the stakes. From what I can tell, her gloves have been bugged since launch, and the fight was likely balanced around them being active and auto-clearing her debuffs. Last time I was there, she got paralyzed early in the first round and they made quick work of her after that (and this was a multiplayer session on Explorer).
Sanctuary does make the fight all but trivial if there's a cleric in the party.