Nitrux uses the Liquorix kernel, described as "an enthusiast Linux kernel designed for uncompromised responsiveness in interactive systems, enabling low latency in A/V production, and reduced frame time deviations in games."

It also uses OpenRC instead of systemd. New in this release is kboot, a utility to switch kernels on-the-fly without needing a reboot, and VMetal, which allows users to run Windows in parallel to Nitrux to provide users of access to Windows software.