Are you using an off the shelf NAS or a DIY? I'm looking for around that much space but the consumer/prosumer grade stuff I've seen doesn't really do what I want (full disk encryption, Linux, ability to customize and host a few applications).
I originally figured I'd just cram 5x12TB drives in a case, RAID5, with my Linux flavor of choice... Then I learned how bad RAID5 is with big disks.
I don't need mirroring or high throughput (home NAS - other device backups and local streaming) but would preferably like a little redundancy... As a treat.
Got any pointers?