If you're planning on upgrading why not just build a brand new PC? Since gaming is generally more hardware demanding leave your current PC for work and build a gaming PC. Putting the two together (especially with how you're using it) you're not only increasing the overall hardware demands but you're also increasing the damage of a potential infection. I'm also pretty sure 2080ti isn't going to last you another 10 years. The problem with the 20 series is that it hasn't aged well. If you get everything else top of the line your system will be bottlenecked by the 2080ti. I would build a separate gaming PC and cut the memory demands to buy a beefier GPU. The current PC I'd continue using as a work station.
Buying DDR4 at the current price is a waste of money so if a new PC isn't an option I wouldn't do anything. 32GB should be enough for what you're doing if you weren't trying to run everything at once.