V2 is about Nehalem. V3 is approximately Haswell (iirc it corresponds to some least common denominator of AMD and Intel from around that time). V4 needs AVX512 (that is really the only difference in enabled instructions compared to V3).
Both my daily driver computers can do v3, but not v4. (I like retro computing, so I also have far older computers that can't even do 64-bit at all, but I don't run modern software on those for the most part.)