I got a new PC a couple months ago, mostly for gaming, and I knew I wanted an immutable distro after hearing about the immutable gaming distros. I went with Kinoite since I have plenty of daily driver stuff I still need to do.

So far, the only big issue I've had was figuring out a way to access apps and a desktop for work that I could only get access with the Windows RDP client and a smart card. Eventually, after a lot of digging through docs I was able to work it out by setting up a Windows VM jump box in Virtual Machine Manager with a few additional command line arguments.

Otherwise, no issues at all. The most tweaking I've had to do to launch a game so far was picking a different version of Proton.