There is.

Do it in humans.

Humans can understand the risks involved. Other animals cannot.

If we're going to fuck something up, it better be on our own species.

Recognition that animal testing is actually pretty fucked up would be a good start toward funding research into alternatives, such as biological computer simulations.

We can simulate complex/chaotic systems, like weather, in nearly real-time, so biosim research is mainly a funding and staffing problem at this point.

Probably we'll still need animal testing for the final phase before human trials, but we can at least reduce the need for it to bare minimums.