listing: all - local
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Eye drops made from pig semen deliver cancer treatment to mice (www.nature.com)
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Nature, Published online: 27 March 2026; doi:10.1038/d41586-026-00982-2

Minuscule particles with the ability to cross hard-to-penetrate barriers can be loaded with drug treatments to target intractable diseases.

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Huge lung-cancer screening campaign boosts early diagnosis (www.nature.com)
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Nature, Published online: 27 March 2026; doi:10.1038/d41586-026-00954-6

A programme that offers scans to smokers between the ages of 55 and 74 detects a large number of early-stage lung tumours.

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Giants of the deep and the wonder of space: Books in Brief (www.nature.com)
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Nature, Published online: 27 March 2026; doi:10.1038/d41586-026-00995-x

Andrew Robinson reviews five of the best science picks.

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4
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Sunken Soviet nuclear submarine’s radioactive release (www.nature.com)
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Nature, Published online: 27 March 2026; doi:10.1038/d41586-026-00953-7

Low levels of radioactive strontium and caesium are emanating from a pipe on the wreck of the Komsomolets.

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Briefing Chat: ‘Zombie cells’ resurrected with new genes (www.nature.com)
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Nature, Published online: 27 March 2026; doi:10.1038/d41586-026-00996-w

Nature staff discuss some of the week's top science news.

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Motherhood derails women’s academic careers — these data reveal how and why (www.nature.com)
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Nature, Published online: 27 March 2026; doi:10.1038/d41586-026-00981-3

Mothers in academia take on considerably more childcare-related responsibilities than do fathers.

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Daily briefing: Earliest known dog genome pushes genetic record back 5,000 years (www.nature.com)
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Nature, Published online: 26 March 2026; doi:10.1038/d41586-026-00992-0

The 15,000-year-old remains of domestic dogs hint at their importance to early communities with different ways of living. Plus, ‘grade inflation’ hits PhDs and how environmental scientists can reinvent their research when funding is scarce.

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Chats with sycophantic AI make you less kind to others (www.nature.com)
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Nature, Published online: 26 March 2026; doi:10.1038/d41586-026-00979-x

Even people who were sceptical of chatbots’ utility fell under the sway of the AI tools’ flattery.

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Trump’s new science advisers include 12 technology chiefs — and one academic (www.nature.com)
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Nature, Published online: 26 March 2026; doi:10.1038/d41586-026-00977-z

Sparse academic presence on the US President’s Council of Advisors on Science and Technology reflects a focus on technology and industry.

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Why labs need a napping room to help you work, rest and play (www.nature.com)
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Nature, Published online: 26 March 2026; doi:10.1038/d41586-026-00549-1

A 30-minute snooze can boost creativity and help banish burnout, says neuroscientist Joseph Jebelli, author of The Brain at Rest.

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History of ‘forever’ chemicals is written in Antarctic snow (www.nature.com)
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Nature, Published online: 26 March 2026; doi:10.1038/d41586-026-00867-4

Data gathered during a 1,200-kilometre polar trek show where PFAS levels are the highest.

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Retraction Note: Multisensory learning binds neurons into a cross-modal memory engram (www.nature.com)
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Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10355-4

Retraction Note: Multisensory learning binds neurons into a cross-modal memory engram

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Why insects aren't huge: a new challenge to a decades-old idea (www.nature.com)
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Nature, Published online: 25 March 2026; doi:10.1038/d41586-026-00976-0

Evidence suggests oxygen levels may not have been limiting factor — plus, CRISPR gives cancer-fighting immune cells an upgrade.

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Can China keep up its extraordinary research growth? (www.nature.com)
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Nature, Published online: 25 March 2026; doi:10.1038/d41586-026-00423-0

Evidence of a pivot towards other sources of funding and collaboration suggest it is looking for ways to maintain its rapid pace of change.

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Genomic history of early dogs in Europe (www.nature.com)
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Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10112-7

Genome-wide analysis shows European dogs existed by 14,200 years ago, were already genetically distinct, received less Neolithic Southwest Asian admixture than humans did and contributed substantially to later European dogs.

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Dominant clones leverage developmental epigenomic states to drive ependymoma (www.nature.com)
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Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10270-8

Single-nucleus chromatin and RNA sequencing identifies epigenetic chromatin domains that confer vulnerability to paediatric brain tumours such as ependymomas, providing insight into the development of such tumours despite ‘quiet’ genomes.

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Ectopic NMDAR expression in cancer unmasks germline-encoded autoimmunity (www.nature.com)
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Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10278-0

NMDAR expression is sufficient to induce B cell recruitment and affinity maturation, resulting in receptor-modulating antibodies that connect anti-cancer immunity and autoimmunity.

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Exposed phosphatidylserine is an inhibitory molecule in T cell exhaustion (www.nature.com)
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Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10266-4

Insights into the mechanism by which phosphatidylserine functions as a non-classical inhibitory molecule during T cell exhaustion, and how phosphatidylserine-targeting antibodies enhance T cell responses are explored.

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Functional hierarchy of the human neocortex across the lifespan (www.nature.com)
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Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10219-x

fMRI data from individuals of a wide range of ages (from a few days to 100 years old) are used to map the key organizational axes of functional connectivity in the human cortex throughout the lifespan.

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Towards intelligent and miniaturized drug delivery devices (www.nature.com)
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Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10221-3

Intelligent and miniaturized drug delivery devices leveraging advances in biotechnology, artificial intelligence, electronics and materials science enable treatments with increased precision and responsiveness, with applications in cancer, diabetes, cardiovascular disease and other diseases.

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Aversive learning hijacks a brain sugar sensor to consolidate memory (www.nature.com)
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Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10306-z

A study in Drosophilareveals a mechanism of non-homeostatic hunger and its critical relevance for memory consolidation.

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Inactivating SnRK1β1A promotes broad-spectrum disease resistance in rice (www.nature.com)
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Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10273-5

SnRK1β1A in rice promotes susceptibility to multiple fungal diseases, and disrupting this infection-inducible gene confers broad-spectrum resistance without compromising growth or yield under normal field conditions.

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Topological soliton frequency comb in nanophotonic lithium niobate (www.nature.com)
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Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10292-2

An integrated lithium niobate–semiconductor platform generates topological soliton frequency combs on-chip, enabling turn-key, dispersion-agnostic comb sources without high-Q resonators or complex stabilization.

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Structural energetics of cold sensitivity (www.nature.com)
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Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10276-2

Data from cryogenic electron microscopy combined with hydrogen–deuterium exchange mass spectrometry inform a mechanism for cold-evoked activation of the TRPM8 channel, providing a structural and energetic framework to explain cold sensitivity.

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A fast starburst wind consumes most of the energy from supernovae (www.nature.com)
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Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10231-1

Starburst galaxies are seen to host galaxy-scale winds, which are super-fast and could be powered entirely by the thermal pressure of gas heated by supernovae.

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